Description
Product details
Glycolyte is available in two different formulations with distinct routes and clinical uses. Glycolyte Injection contains Glycopyrrolate Injection USP, an anticholinergic (antimuscarinic) medicine. Injectable glycopyrrolate is used in certain perioperative settings to reduce salivary, pharyngeal, and respiratory secretions and may also be used with specific medicines during reversal of neuromuscular blockade. Glycolyte Respule contains Glycopyrronium Inhalation Solution, an inhaled long-acting muscarinic antagonist (LAMA). Glycopyrronium inhalation formulations are used for maintenance bronchodilation in obstructive airway disease, depending on the specific product's approved indication. Although glycopyrrolate and glycopyrronium refer to closely related naming of the same active moiety, the injection and inhalation formulations are not interchangeable. Available Forms Product Active Ingredient Dosage Form Glycolyte Injection Glycopyrrolate Injection USP Injection Glycolyte Respule Glycopyrronium Inhalation Solution / Respule The exact concentration and pack size should be confirmed from each product label. Dosage Glycolyte Injection The dose should be determined by a healthcare professional according to the clinical indication, patient's age and body weight, concurrent medicines, and overall medical condition. It should be administered only by appropriately trained healthcare professionals according to the approved product instructions. Glycolyte Respule The inhalation solution should be used with the appropriate nebulization/inhalation device as specified for the product. Dose and frequency depend on the labeled strength, indication, and physician's prescription. The contents of a respule are not intended for injection or oral administration. Precautions Inform the doctor about glaucoma, urinary retention, prostate problems, intestinal obstruction, or significant heart conditions. Use cautiously in patients susceptible to anticholinergic effects. Tell the healthcare professional about other anticholinergic medicines being used. Avoid accidental contact of nebulized medication with the eyes. Pregnancy and breastfeeding require medical assessment. The inhalation formulation should be used only with the recommended delivery system. Do not interchange the injectable and inhalation formulations. Side Effects Possible anticholinergic side effects include: Dry mouth Constipation Headache Dizziness Blurred vision Increased heart rate Difficulty urinating Inhaled glycopyrronium may additionally cause: Cough Throat irritation Upper respiratory symptoms Rarely, serious hypersensitivity or paradoxical bronchospasm may occur after inhalation.
