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Itrotab 100 & Itrotab 200 Capsules Generic Name: Itraconazole Description Itrotab 100 Capsules and Itrotab 200 Capsules contain Itraconazole, a broad-spectrum triazole antifungal medicine used for the treatment of various fungal infections caused by susceptible organisms. Itraconazole works by inhibiting the fungal enzyme involved in the production of ergosterol, an essential component of the fungal cell membrane. This disrupts fungal cell-membrane function and helps stop fungal growth. Depending on the diagnosis and approved indication, itraconazole may be prescribed for certain skin, nail, oral, vaginal, and systemic fungal infections. Available Strengths Product Active Ingredient Strength Itrotab 100 Capsules Itraconazole 100 mg Itrotab 200 Capsules Itraconazole 200 mg Dosage The dosage and duration of treatment should be determined by a healthcare professional according to: Type and location of fungal infection Severity of infection Patient's overall health Liver function Other medicines being taken Clinical response Itraconazole capsules are generally taken immediately after a full meal to improve absorption. Medicines that reduce stomach acidity can affect the absorption of itraconazole capsules. Patients should complete the prescribed treatment course and should not change the dose without medical advice. Precautions Inform the doctor about liver disease, heart failure, or other significant heart conditions. Liver-function monitoring may be appropriate during treatment. Tell the healthcare professional about all medicines and supplements being used because itraconazole has many clinically important drug interactions. Acid-reducing medicines can affect absorption of itraconazole capsules. Pregnancy requires careful medical assessment. Do not interchange itraconazole capsules with other itraconazole formulations without professional advice because their absorption may differ. Seek medical advice if unusual fatigue, dark urine, persistent nausea, or yellowing of the skin/eyes occurs. Side Effects Possible side effects include: Nausea Abdominal discomfort Headache Diarrhea Constipation Dizziness Indigestion Skin rash More serious adverse effects can include liver injury, severe hypersensitivity reactions, heart failure, and clinically significant drug interactions. Warning Itrotab Capsules are prescription antifungal medicines and should be used under medical supervision. Itraconazole can cause or worsen congestive heart failure in susceptible patients. Symptoms such as shortness of breath, unusual swelling, or rapid unexplained weight gain require prompt medical evaluation FAQ 1. What are Itrotab Capsules used for? They are used for the treatment of certain fungal infections caused by organisms susceptible to itraconazole. 2. What strengths are available? Itrotab is available in the listed strengths of 100 mg and 200 mg. 3. How does Itraconazole work? It inhibits fungal ergosterol synthesis, disrupting the fungal cell membrane and preventing fungal growth. 4. Should Itrotab Capsules be taken with food? Itraconazole capsules are generally taken immediately after a full meal to support absorption, unless the specific product instructions state otherwise. 5. Can Itraconazole affect the liver? Yes. Itraconazole can rarely cause serious liver injury, so symptoms such as jaundice, dark urine, or unusual persistent fatigue require medical attention. 6. Does Itraconazole interact with other medicines? Yes. Itraconazole is a strong inhibitor of CYP3A4 and can interact with numerous medicines. A healthcare professional should review the patient's medications before treatment. 7. Can patients with heart failure take Itrotab? Itraconazole can cause or worsen congestive heart failure, so its use in patients with ventricular dysfunction requires careful assessment and may be contraindicated for certain indications.
